(Received 5 April 1978; accepted 26 May 1978)
Published Online: January
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The polymorphism of the phosphoglucomutase (PGM) system was first demonstrated by starch gel electrophoretic studies conducted by Spencer et al  on the enzyme from the human red cell. Pedigree studies  have shown that two common autosomal alleles PGM11 and PGM12 situated on the same locus of chromosome 1  are responsible for determining the three common phenotypes PGM1 1, PGM1 2, and PGM1 2–1 that are observed by starch gel electrophoresis.
Senior scientific officer, Home Office Central Research Establishment, Aldermaston, Reading, Berkshire
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