(Received 22 August 1975; accepted 15 December 1975)
Published Online: 1976
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Recent publications [1–8] have emphasized that the use of local anesthetic substances is not entirely without risk to the patient and have stressed the difficulty in establishing what is the maximum safe dosage in any particular clinical situation. A search of the literature indicates that few reports are available on blood and tissue concentrations in fatalities after therapeutic misadventure with lidocaine or other local anesthetic agents.
Armed Forces Institute of Pathology, Washington, D.C.
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