ASTM WK73235

    New Test Method for Determination of Polyfluoroalkyl Substances (PFAS) in Aqueous Matrices by Cosolvation followed by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)

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    Developed by Subcommittee: D19.06 | Committee D19 | Contact Staff Manager



    WK73235

    1. Scope

    1.1 This procedure covers the determination of per- and polyfluoroalkyl substances (PFASs) in aqueous matrices using liquid chromatography (LC) and detection with tandem mass spectrometry (MS/MS). These analytes are cosolvated by a 1+1 ratio of sample and methanol then qualitatively and quantitatively determined by this test method. Quantitation is by a technique known as selected reaction monitoring (SRM) or sometimes referred to as multiple reaction monitoring (MRM). 1.2 The method detection limit (MDL) and reporting range for the target analytes are listed in Table 1. The target concentration for the reporting limit for this test method was 3.14 times the MDL, or may be arbitrarily set at the lowest calibration standard (5ng/L for most analytes). 1.2.1 The reporting limit in this test method is the minimum value below which data are reported as non-detects. The reporting limit is calculated as 3.18 times the 40 CFR part 136 Appendix B calculated MDL, or as the lowest calibration standard. The reporting limit may be lowered assuming the minimum performance requirements of this test method at the lower concentrations are met. Depending on data usage, this test method may be performance based and modifications that improve performance while still meeting method quality acceptance criteria are allowed. Analyte detections between the method detection limit and the reporting limit are estimated concentrations. In most cases, the reporting limit is the concentration of the Level 1 calibration standard as shown in Table 4. 1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.5 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.


    Keywords

    environmental, EPA, PFAS, wastewater, drinking water

    Rationale

    This definitive method expands on D7979 for qualitative and quantitative analysis of PFAS compounds including new target analytes from EPA Methods 533 and 537.1 plus additional compounds. Intended users are environmental laboratories and regulators.

    The title and scope are in draft form and are under development within this ASTM Committee.

    Citing ASTM Standards
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    Work Item Status

    Date Initiated:
    06-09-2020

    Technical Contact:
    William Lipps

    Status:
    Draft Under Development