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ASTM E2897 - 12
Standard Guide for Evaluation of the Effectiveness of Hand Hygiene Topical Antimicrobial Products using ex vivo Porcine Skin
Significance and Use
5.1 The guide may be used to demonstrate the effectiveness of topical antimicrobial products using pigskin as a surrogate for human skin and the cup scrub technique for sampling.
5.2 The techniques described can be used to simulate Test Method E1174 and will use the pigskin substrate to overcome limitations posed by exposure of human subjects to potentially pathogenic microorganisms, while offering the benefit of applicability to a wide variety of hand-washing conditions that cannot be simulated in test tubes.
5.3 Use of the pigskin surrogate offers less expensive and higher throughput screening.
1.1 This guide is designed to demonstrate the effectiveness of hand hygiene topical antimicrobial products using pigskin as a surrogate model.
1.2 Knowledge of microbiological techniques is required for these procedures.
1.3 This standard guide can be used to evaluate topical antimicrobial handwash or handrub formulations.
1.4 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.
1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.
E1054 Test Methods for Evaluation of Inactivators of Antimicrobial Agents
E1174 Test Method for Evaluation of the Effectiveness of Health Care Personnel Handwash Formulations
E1874 Test Method for Recovery of Microorganisms From Skin using the Cup Scrub Technique
ICS Number Code 07.100.99 (Other standards related to microbiology); 71.100.35 (Chemicals for industrial and domestic desinfection purposes)
Referencing This Standard
ASTM International is a member of CrossRef.
ASTM E2897-12, Standard Guide for Evaluation of the Effectiveness of Hand Hygiene Topical Antimicrobial Products using ex vivo Porcine Skin, ASTM International, West Conshohocken, PA, 2012, www.astm.org
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