ASTM E2548 - 16

    Standard Guide for Sampling Seized Drugs for Qualitative and Quantitative Analysis

    Active Standard ASTM E2548 | Developed by Subcommittee: E30.01

    Book of Standards Volume: 14.02

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    Significance and Use

    3.1 This guide provides information for the sampling of seized-drug submissions.

    3.2 The principal purpose of sampling in the context of this guide is to answer relevant questions about a population by examination of a portion of the population. For example:


    What is the net weight of the population?


    What portion of the units of a population can be said to contain a given drug at a given level of confidence?

    3.3 By developing a sampling strategy and implementing appropriate sampling schemes, as illustrated in Fig. 1, a laboratory will minimize the total number of required analytical determinations, while ensuring that all relevant legal and scientific requirements are met.

    1. Scope

    1.1 This guide covers minimum considerations for sampling of seized drugs for qualitative and quantitative analysis.

    1.2 This guide cannot replace knowledge, skill, or ability acquired through appropriate education, training, and experience and should be used in conjunction with sound professional judgment.

    2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.

    ASTM Standards

    E105 Practice for Probability Sampling of Materials

    E122 Practice for Calculating Sample Size to Estimate, With Specified Precision, the Average for a Characteristic of a Lot or Process

    E141 Practice for Acceptance of Evidence Based on the Results of Probability Sampling

    E1732 Terminology Relating to Forensic Science

    E2329 Practice for Identification of Seized Drugs

    E2334 Practice for Setting an Upper Confidence Bound For a Fraction or Number of Non-Conforming items, or a Rate of Occurrence for Non-conformities, Using Attribute Data, When There is a Zero Response in the Sample

    ISO Standards

    ISO 3534-1

    ISO 3534-2 Statistics Vocabulary and Symbols Part 2: Statistical Quality Control

    ICS Code

    ICS Number Code 11.100.30 (Analysis of blood and urine)

    UNSPSC Code

    UNSPSC Code 41115813(Toxicology analyzers)

    Referencing This Standard
    Link Here
    Link to Active (This link will always route to the current Active version of the standard.)

    DOI: 10.1520/E2548-16

    ASTM International is a member of CrossRef.

    Citation Format

    ASTM E2548-16, Standard Guide for Sampling Seized Drugs for Qualitative and Quantitative Analysis, ASTM International, West Conshohocken, PA, 2016,

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