ASTM E2169 - 12

    Standard Practice for Selecting Antimicrobial Pesticides for Use in Water-Miscible Metalworking Fluids

    Active Standard ASTM E2169 | Developed by Subcommittee: E34.50

    Book of Standards Volume: 11.03


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    Significance and Use

    5.1 This practice summarizes the steps in the antimicrobial pesticide selection process, reviewing technical and regulatory considerations inherent in the process. It complements and amplifies information provided in Practice E1497.

    5.1.1 Steps in the antimicrobial selection process include: needs identification, use strategy selection, efficacy testing, chemical compatibility testing, regulatory consideration review, handling and disposal issue review.

    5.2 This practice provides stakeholders in the microbicide selection process an overview of its complexities, including the process of obtaining pesticide registration from cognizant governing bodies.

    5.3 Personnel responsible for antimicrobial pesticide selection will be able to use this practice as a roadmap through the process.

    5.4 Personnel responsible for industrial hygiene, product or plant management will gain insight to the tradeoffs attendant with antimicrobial use and selection.

    1. Scope

    1.1 This practice provides recommendations for selecting antimicrobial pesticides (microbicides) for use in water-miscible metalworking fluids (MWF). It presents information regarding regulatory requirements, as well as technical factors including target microbes, efficacy and chemical compatibility.

    1.2 This guide is not an encyclopedic compilation of all the concepts and terminology uses by chemists, microbiologists, toxicologists, formulators, plant engineers and regulatory affairs specialists involved in antimicrobial pesticide selection and application. Instead, it provides a general understanding of the selection process and its supporting considerations.

    1.3 The values in SI units are to be regarded as the standard.

    1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.


    2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.

    ASTM Standards

    D1067 Test Methods for Acidity or Alkalinity of Water

    D1293 Test Methods for pH of Water

    D3519 Test Method for Foam in Aqueous Media (Blender Test)

    D3946 Test Method for Evaluating the Bacteria Resistance of Water-Dilutable Metalworking Fluids

    D4478 Test Methods for Oxygen Uptake

    D5465 Practice for Determining Microbial Colony Counts from Waters Analyzed by Plating Methods

    E686 Method for Evaluation of Antimicrobial Agents in Aqueous Metal Working Fluids

    E1302 Guide for Acute Animal Toxicity Testing of Water-Miscible Metalworking Fluids

    E1326 Guide for Evaluating Nonconventional Microbiological Tests Used for Enumerating Bacteria

    E1497 Practice for Selection and Safe Use of Water-Miscible and Straight Oil Metal Removal Fluids

    E2144 Practice for Personal Sampling and Analysis of Endotoxin in Metalworking Fluid Aerosols in Workplace Atmospheres


    ICS Code

    ICS Number Code 65.100.01 (Pesticides and other agrochemicals)

    UNSPSC Code

    UNSPSC Code 93141808(Occupational health or safety services)


    DOI: 10.1520/E2169-12

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