ASTM E1373-01(2005)e1

Withdrawn Rationale:

This test method determines the no observed-effect level (NOEL) and toxic effects associated with continuous or repeated inhalation exposure to a chemical, pesticide, or mixture for a period of 90 days. The test is not capable of determining those effects that have a long latency period for development (for example, carcinogenicity and life shortening).

Formerly under the jurisdiction of Committee E47 on Biological Effects and Environmental Fate, this test method was withdrawn in November 2009. This standard is being withdrawn with no replacement because other more appropriate methods exist.

1.1 This test method determines the no observed-effect level (NOEL) and toxic effects associated with continuous or repeated inhalation exposure to a chemical, pesticide, or mixture for a period of 90 days. The test is not capable of determining those effects that have a long latency period for development (for example, carcinogenicity and life shortening).

1.2 This test method which is applicable to a gas, vapor, aerosol, or particulate is conducted after initial information on toxicity is obtained by acute testing.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

aerodynamic diameter; blood chemistry; cumulative toxicity; geometric mean diameter; geometric standard deviation; head-only exposure; hematology; histopathology; inhalable diameter; inhalation; inhalation chamber; median diameter; nasal exposure; necropsy; particle size distribution; pesticide; rat; subchronic; toxicity; urinalysis;

Citing ASTM Standards

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