ASTM E1055-99(2003)

Withdrawn Rationale:

This test method determines the duration and the numerical degree of eye irritation in young, adult albino rabbits. The test is an alternative method to the standard Draize eye irritation method. Experimentation indicates that this procedure provides more realistic data, and therefore a better basis for making predictions of eye responses from accidental exposure in man. This test method is applicable to both liquids and solids; it is not applicable to aerosols or vapors.

Formerly under the jurisdiction of Committee E47 on Biological Effects and Environmental Fate, this test method was withdrawn in February 2010, because other guidelines currently exist.

1.1 This test method determines the duration and the numerical degree of eye irritation in young, adult albino rabbits. The test is an alternative method to the standard Draize eye irritation method. Experimentation indicates that this procedure provides more realistic data, and therefore a better basis for making predictions of eye responses from accidental exposure in man. This test method is applicable to both liquids and solids; it is not applicable to aerosols or vapors.

1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility the user of this standard to establish appropriate safety and health practices and determine the applicability and regulatory limitations prior to use.

Keywords

chemicals; Draize method; eye; irritation; pesticides; rabbit

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