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Significance and Use
4.1 The purity of water is relative and is usually characterized by the limits of impurities found in the water as well as by the methods used to prepare and handle the water. Section 7 mentions the suitable methods for water preparation.
1.1 This guide is intended to describe the chemical and biological characteristics of water to be used whenever critical purity is essential to the use intended in laboratory Bio-Applications, for example, clinical, pharmaceutical, and biomedical. The importance of such a reagent is often underestimated despite the impact that it can have.
1.2 This guide is not intended to be used as a reference in preparing water for injectables. Generally, the appropriate use of this guide may include experiments involving tissue culture, chromatography, mass spectrometry, Polymerase Chain Reaction (PCR), DeoxyriboNucleic Acid (DNA) sequencing, DNA hybridization, electrophoresis, molecular biology or analyses where molecular concentrations of impurities may be important.
2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.
D1125 Test Methods for Electrical Conductivity and Resistivity of Water
D1129 Terminology Relating to Water
D1193 Specification for Reagent Water
D4453 Practice for Handling of High Purity Water Samples
D5127 Guide for Ultra-Pure Water Used in the Electronics and Semiconductor Industries
D5173 Test Method for On-Line Monitoring of Carbon Compounds in Water by Chemical Oxidation, by UV Light Oxidation, by Both, or by High Temperature Combustion Followed by Gas Phase NDIR or by Electrolytic Conductivity
D5245 Practice for Cleaning Laboratory Glassware, Plasticware, and Equipment Used in Microbiological Analyses
D5391 Test Method for Electrical Conductivity and Resistivity of a Flowing High Purity Water Sample
D5542 Test Methods for Trace Anions in High Purity Water by Ion Chromatography
D5673 Test Method for Elements in Water by Inductively Coupled Plasma--Mass Spectrometry
D5996 Test Method for Measuring Anionic Contaminants in High-Purity Water by On-Line Ion Chromatography
F1094 Test Methods for Microbiological Monitoring of Water Used for Processing Electron and Microelectronic Devices by Direct Pressure Tap Sampling Valve and by the Presterilized Plastic Bag Method
ICS Number Code 71.060.01 (Inorganic chemicals in general)
ASTM D5196-06(2013), Standard Guide for Bio-Applications Grade Water, ASTM International, West Conshohocken, PA, 2013, www.astm.orgBack to Top