Allelic distribution of four tetranucleotide repeat loci (D3S1358, D18S51, D19S253, and FGA) in a population from Porto (North Portugal)
Pinheiro, F
Forensic scientists, ICBAS, Medico-Legal Institute, Porto, Portugal

Pontes, L
Forensic scientists, ICBAS, Medico-Legal Institute, Porto, Portugal

da Costa, JP
Forensic scientists, ICBAS, Medico-Legal Institute, Porto, Portugal

Huguet, E
Associate professor and professor, respectively, Forensic Genetics Laboratory, Legal medicine Department, School of Medicine, University of Barcelona, Barcelona, Spain

Moreno, P
Professor, Animal Biology Department, Section of Anthropology, School of Biology, University of Barcelona, Barcelona, Spain

Gené, M
Associate professor and professor, respectively, Forensic Genetics Laboratory, Legal medicine Department, School of Medicine, University of Barcelona, Barcelona, Spain


Abstract
Allele frequencies for four short tandem repeat loci were determined in a population sample from Porto (North Portugal), using the polymerase chain reaction (PCR), in order to investigate possible genetic differences between populations from the center and north of Portugal. After denaturing PAGE electrophoresis, nine alleles were identified for D3S1358 (n 5 256), 13 alleles for D18S51 (n 5 235), 10 alleles for D19S253 (n 5 238), and 15 alleles for FGA (n 5 181). No deviations from Hardy-Weinberg equilibrium were found. The allele frequencies observed are similar to those of the Portuguese population compared except for the D3S1358 system.

Keywords:
allele frequencies, D18S51, D19S253, D3S1358, DNA typing, FGA, forensic science, population genetics, Portugal

Paper ID: JFS4540891

ASTM International is a member of CrossRef.
Author Thompson, WC Affiliation Department of Criminology, University of California, Irvine, CA 92697-7080 Author Taroni, F Affiliation School of Criminal Science, BCH, University of Lausanne, 1015 Lausanne-Dorigny, Switzerland. Author Aitken, CGG Affiliation School of Mathematics, The University of Edinburgh, Mayfield Road, Edinburgh EH9 3JZ, United Kingdom. Author Pinheiro F, Pontes L, da Costa JP, Huguet E, Moreno P, Gené M Title Allelic distribution of four tetranucleotide repeat loci (D3S1358, D18S51, D19S253, and FGA) in a population from Porto (North Portugal) Symposium , Committee on