Fire hazards are inherent in oxygen systems. Therefore, a systematic approach to identify and address these fire hazards is essential to protecting personnel and equipment. The oxygen compatibility assessment process (previously known as the oxygen hazards analysis process) designed by NASA Johnson Space Center White Sands Test Facility can be used to determine the presence of fire hazards in oxygen systems and the likelihood of a fire. This process may be used as both a design guide and an approval process. The procedure for performing an oxygen compatibility assessment is a structured step-by-step process to: determine the most severe operating conditions; assess the flammability of the system materials at the use conditions; evaluate the presence and efficacy of ignition mechanisms; assess the potential for a fire to breach the system; and determine the reaction effect (the potential loss of life, mission, and system functionality as the result of a fire). This process should be performed for each component in a system. The results of each component assessment should be recorded in an Oxygen Compatibility Assessment Table. In addition, a summary of the overall assessment should be provided in a Hazard Control Table, which provides a convenient way for readers of the document to know the hazards that exist within the entire system and the status of whether or not the recommendations have been implemented.