Howmedica developed the Titanium-12Molybdenum-6Zirconium-2Iron beta titanium alloy (also known as TMZF beta titanium alloy) in the late 1980s. Two patents were issued for this high strength, low modulus, ductile, biocompatible, titanium base alloy [1,2]. The mechanical properties for wrought machining and forging bar in ASTM F 1813 show higher tensile and yield strengths than Ti-6A1-4V ELI (ASTM F 136), the most widely used titanium grade for medical and surgical implant applications. According to the ASTM standard, the TMZF alloy also has improved ductility over Ti-6A1-4V ELI, which is to be expected when comparing beta and alpha+beta titanium alloys. TMZF alloy offers higher tensile strength and greater flexibility than Ti-6A1-4Valloy. Data are presented for semi-finished TMZF mill product forms in the solution-annealed condition. The influence of oxygen as an interstitial strengthening element is shown for Ti-12Mo-6Zr-2Fe and compared with common titanium alloys used in or being considered for use in the medical device industry.