SEDL / STP / STP752-EB / STP35154S

Method for Analysis of Rat Acceptance Data Generated in Anticoagulant Bait Bioassays

Palmateer, SD
Supervisory biologist, Terrestrial and Aquatic Biology Unit, U.S. Environmental Protection Agency, Beltsville, Md.

Pages: 6    Published: Jan 1981

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Abstract

A possible method for interpreting data generated in rat free-choice bioassays with anticoagulatn rodenticides is described. The method allows a greater freedom in interpretation of parameters of efficacy but has a slight problem in differences in bait acceptance by male and female rats. Basically, analysis is a simple one-tailed t-test comparing percent bait acceptance with a cutoff point. The use of the method is demonstrated with authentic data developed by the U.S. Environmental Protection Agency.