Linear elastic fracture mechanics has been used to perform a fatigue evaluation of a Canadian Deuterium Uranium (CANDU) reactor end fitting. An initial hypothetical flaw shape was assumed at a critical part of the end fitting. The effect of residual stress on the fatigue crack growth was accounted for through a growth rate model which had both range of stress intensity and maximum stress intensity as its parameters. The analysis showed that the fatigue crack growth during the estimated life of a reactor is so small that it is nearly negligible.