SEDL / STP / STP953-EB / STP25247S

Grafts of HTR Polymer Versus Kiel Bone in Experimental Long Bone Defects in Rats

Binderman, I
Head, associate professor, professor of surgery, and laboratory assistant, Hard Tissue Laboratory, Ichilov Medical Center, Sackler Medical School, Tel Aviv,

Goldstein, M
Head, associate professor, professor of surgery, and laboratory assistant, Hard Tissue Laboratory, Ichilov Medical Center, Sackler Medical School, Tel Aviv,

Horowitz, I
Head, associate professor, professor of surgery, and laboratory assistant, Hard Tissue Laboratory, Ichilov Medical Center, Sackler Medical School, Tel Aviv,

Fine, N
Head, associate professor, professor of surgery, and laboratory assistant, Hard Tissue Laboratory, Ichilov Medical Center, Sackler Medical School, Tel Aviv,

Taicher, S
Professor and chief, Hebrew University—Hadassah Medical Center, Jerusalem,

Ashman, A
Former head of dental researchassociate professor, Mount Sinai HospitalNew York University College of Dentistry, New YorkNew York, NY

Shteyer, A
Professor and chief, Hebrew University—Hadassah Medical Center, Jerusalem,

Pages: 7    Published: Jan 1987

Download this paper for $25 PDF (288K)          View License Agreement
Abstract

Gaps were prepared surgically in femora of 42 albino rats, and were kept apart by a looped wire. Grafts of Kiel bone (KB) and HTR™ polymer in different environments were implanted into those gaps. The control groups showed a nonbony healing 36 days after the osteotomy. KB or HTR polymer alone failed to induce bone bridging, while KB with autologous bone marrow induced bone bridging in the gaps. The most significant finding in this study was the ability of calcium hydroxide [Ca(OH)²] grafted with either KB or HTR polymer to cause differentiation of bone matrix in the surgical gaps. The combination of HTR polymer and Ca(OH)² induced formation of trabecular bone bridging to a greater extent than all the other material combinations.