Two enclosed plasma spectrometry sources [Applied Research Laboratories (ARL) 35000 and Sopra inductive plasma spectrometer 1500] are described with emphasis on specific designs and safety devices. One of these spectrometers has been working routinely on toxic and high-alpha-emitting samples for five years. The glove box adaptation results in only a small decrease in sensitivity and no visible effect on the precision obtained. The main applications are determinations of trace impurities in plutonium, neptunium, and beryllium, and simultaneous determination of americium and plutonium in dilute solutions.