STP1344: Determination of Radionuclides in Biological Fluids Using a High Resolution ICP-MS in Low Resolution Mode

    Pickford, CJ
    R & D manager, manager - Inorganic Analysis, and senior analyst, AEA Technology/ Analytical Services, Didcot, Oxfordshire

    Haines, J
    R & D manager, manager - Inorganic Analysis, and senior analyst, AEA Technology/ Analytical Services, Didcot, Oxfordshire

    Heam, R
    R & D manager, manager - Inorganic Analysis, and senior analyst, AEA Technology/ Analytical Services, Didcot, Oxfordshire

    McAughey, J
    Manager, Health-Related Aerosols, AEA Technology, Didcot, Oxfordshire

    Pages: 9    Published: Jan 1998


    Abstract

    High Resolution (HR) ICP-MS in low resolution mode was used with ultrasonic nebulization to determine long-lived radionuclides and surrogates in human body fluid samples. Although very sensitive, achieving LODs less than 0.1 fg/mL for 244Pu, a number of molecular ion interferences have been encountered from commonly-occurring species which limit sensitivity and require the development of specialized sample preparation routes.

    Keywords:

    ICP-MS, high resolution, trace analysis, biological samples, radiochemical methods, plutonium, lanthanoids


    Paper ID: STP15731S

    Committee/Subcommittee: C26.09

    DOI: 10.1520/STP15731S


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