SEDL / STP / STP1396-EB / STP15297S

Evaluation of Adhesive and Absorption Properties for Absorbable Tissue Adhesives

Allan, JM
Manager of bioengineering and materials research, research engineer, staff scientist, director of research and development, Poly-Med, Inc., Pendleton, SC

Flagle, JA
Manager of bioengineering and materials research, research engineer, staff scientist, director of research and development, Poly-Med, Inc., Pendleton, SC

Kline, JD
Manager of bioengineering and materials research, research engineer, staff scientist, director of research and development, Poly-Med, Inc., Pendleton, SC

Dooley, RL
Dept. Chair, Clemson University, Clemson, SC

Shalaby, SW
Manager of bioengineering and materials research, research engineer, staff scientist, director of research and development, Poly-Med, Inc., Pendleton, SC

Pages: 4    Published: Jan 2000

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Abstract

Absorbable tissue adhesives for wound repair have gained interest in recent years compared with traditional devices for wound closure such as sutures and staples. while the demand for tissue adhesives continues to increase, in vitro methods for their evaluation remain scarce. The lack of a widely accepted method for evaluation of tissue adhesives and the availability of a family of novel absorbable tissue adhesive systems provided an incentive to develop a test method for assessing the two key parameters of candidate adhesives, namely adhesive strength and absorption. This report describes a new method for determining the absorption characteristics and adhesive strength of methoxypropyl cyanoacrylate-oxalate formulations.