SEDL / STP / STP1205-EB / STP13115S

Modeling of Human Exposure/Dose to Benzene

Behar, JV
Environmental scientist and research biologist, Environmental Monitoring Systems Laboratory (EMSL), Las Vegas, NV

Blancato, JN
Environmental scientist and research biologist, Environmental Monitoring Systems Laboratory (EMSL), Las Vegas, NV

Pandian, MD
Environmental engineer, Harry Reid Center for Environmental Studies, UNLV, Las Vegas, NV

Thomas, J
Statistician, Information Systems and Services, Inc., Las Vegas, NV

Pages: 11    Published: Jan 1993

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Abstract

This paper presents the latest developments in the modeling of population exposures to airborne pollutants in indoor environments. Population exposure estimates are composed of three basic components: (1) human activity patterns, (2) microenvironmental (primarily indoor) concentration distributions, and (3) ambient (primarily background or outdoor) concentration distributions. Human activity pattern data and concentration distribution data may be derived from experiments or by simulation. This paper reports the progress made in combining the above three components of exposure in a simulation model. Exposure estimation is a precursor to dose determination. The latest results in our attempts to incorporate pharmacokinetic modules into human exposure models are presented.