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Head Injured Patients Who Talk Before Deterioration or Death: The TADD Syndrome
Ommaya AK, Thibault LE, Boock RJ, Meaney DF


Pages: 17    Published: Jan 1994


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Source: STP1229-EB


Abstract
A review of a class of head injured patients who display a lucid interval before onset of coma which defines an important category of brain trauma. A hypothesis explaining the mechanism of this syndrome (T.A.D.D.) is developed on the basis of in-vitro testing of venous and arterial responses to tensile strains and the relevant clinico-pathologic data are reviewed. Venospasm is proposed as the cause of secondary ischemic hypoxia associated with a high incidence of acute subdural hematomas and brain swelling. Suggestions for further testing of this hypothesis and implications for preventive management are discussed.


Keywords:
Venospasm, lucid interval, brain injury mechanisms, acute subdural hematoma, tensile strain, blood vessels, brain swelling

Paper ID: STP12820S
Committee/Subcommittee: F08.51
DOI: 10.1520/STP12820S
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