SEDL / STP / STP1312-EB / STP11345S

Solvent Effects in Degradation Kinetics of Emamectin Benzoate

Peterson, RF
Senior Research Fellow, Technician, Associate Director, Merck Research Laboratories, Three Bridges, NJ

Alvarez, MD
Senior Research Fellow, Technician, Associate Director, Merck Research Laboratories, Three Bridges, NJ

Mookerjee, PK
Senior Research Fellow, Technician, Associate Director, Merck Research Laboratories, Three Bridges, NJ

Pages: 9    Published: Jan 1996

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Abstract

Avermectins are fermentation products with unique insecticidal properties which are useful in crop protection, animal health and human health. In this study, the degradation kinetics of MK-0244, a potent lepidoptericidal avermectin, were examined over a range of temperatures in selected solvents useful in crop protection. Data on initial solvolysis rates were used to obtain mechanistic and kinetic information about the degradation of MK-0244 under solvolytic conditions.