STP1007

    Use of Aquatic Lethality Tests to Estimate Safe Toxicant Concentrations for Initial Ecological Risk Assessments

    Published: Jan 1988


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    Abstract

    This article presents an approach which allows the body of comparative toxicity data to be used in initial ecological risk assessments to extrapolate from an acute test with an indicator species to an estimate of the no-effect concentration in the environment. The fathead minnow (Pimephales promelas) acute value was selected as the reference value since this ecotoxicity endpoint has the largest data base for comparative toxicity comparisons. Comparative toxicity endpoints for fish and invertebrates were collected from various sources. When data for all ecotoxicity endpoints are plotted for all chemicals, this plot can be analyzed statistically using regression analysis to calculate an equation defining the upper 95 percentile prediction limit. The upper 95% prediction limit uses the reference test (fathead 96-h acute value) to calculate a concentration that would be safe for 95% of the species and chemicals, assuming that enough comparative toxicological data (especially chronic endpoints) are included in the data set.

    Keywords:

    risk assessment, comparative toxicity, fish, invertebrates, fathead minnow, aquatic toxicology


    Author Information:

    Holcombe, GW
    Research aquatic biologists and director, Environmental Research Laboratory—Duluth, U.S. Environmental Protection Agency, Duluth, MN

    Phipps, GL
    Research aquatic biologists and director, Environmental Research Laboratory—Duluth, U.S. Environmental Protection Agency, Duluth, MN

    Veith, GD
    Research aquatic biologists and director, Environmental Research Laboratory—Duluth, U.S. Environmental Protection Agency, Duluth, MN


    Paper ID: STP10306S

    Committee/Subcommittee: E47.01

    DOI: 10.1520/STP10306S


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