Chapter 15-The Development of Coralline Porous Ceramic Graft Substitutes

    Published: Jan 2003

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    BONE, UNLIKE MOST TISSUES, HAS a unique ability to regenerate, reforming completely without a scar. Surgeons have learned over the centuries to capitalize on this natural and invaluable attribute for the repair of large defects or to generate bone where it does not normally form. Autograft is the undisputed “gold standard” today for generating or regenerating bone. Over 250,000 autograft procedures are performed annually for orthopedic and neurosurgical treatments in the United States alone. However, autografting is not without disadvantages. Clinical studies show that it causes increased donor site morbidity to the patient, such as pain, blood loss, and scarring [1]. In addition, harvesting bone adds additional operating room time to the procedure. Further, the volume or quantity of autograft may be limited. Therefore, other bone grafting materials have been developed.

    Author Information:

    Agrawal, M

    Katti, DS

    Shors, EC
    Research and New Technology, Interpore Cross International, Irvine, CA

    Paper ID: MONO10073M

    Committee/Subcommittee: F04.13

    DOI: 10.1520/MONO10073M

    CrossRef ASTM International is a member of CrossRef.

    ISBN10: 0-8031-3356-1
    ISBN13: 978-0-8031-3356-3