MONO6

    Chapter 13-Bone Graft Substitutes: Basic Information for Successful Clinical Use with Special Focus on Synthetic Graft Substitutes

    Published: Jan 2003

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    Abstract

    BONE GRAFTING TECHNIQUES ARE USED in many fields of surgery including orthopedic and trauma surgery, periodontal surgery, and maxillofacial surgery. The need to replace bone lost in chronic disease, infection or trauma is clear, and the field has expanded considerably since substitutes were first used to supplement or replace autologous or allogeneic bone grafting. As a result, the number of choices continues to increase as new materials are developed. However, the rationale for selection of one material over another is not yet clear in many clinical situations. This is in part due to the lack of information on basic bone biology as it applies to implant materials in general, and to a particular clinical application. The purpose of this review is to introduce the variety of bone graft materials currently available, discuss some of the new materials under development, and provide a biological rationale for the outcome when these materials are used clinically in orthopedics.


    Author Information:

    Agrawal, M

    Katti, DS

    Boyan, BD
    Georgia Tech and Emory University, Atlanta, GA

    University of Texas Health Science Center at San Antonio, San Antonio, TX

    McMillan, J
    Georgia Tech and Emory University, Atlanta, GA

    Lohmann, CH
    University of Texas Health Science Center at San Antonio, San Antonio, TX

    University of Hamburg Eppendorf, Hamburg,

    Ranly, DM
    Georgia Tech and Emory University, Atlanta, GA

    Schwartz, Z
    Georgia Tech and Emory University, Atlanta, GA

    University of Texas Health Science Center at San Antonio, San Antonio, TX

    Hebrew University Hadassah, Jerusalem,


    Paper ID: MONO10071M

    Committee/Subcommittee: F04.48

    DOI: 10.1520/MONO10071M


    CrossRef ASTM International is a member of CrossRef.

    ISBN10: 0-8031-3356-1
    ISBN13: 978-0-8031-3356-3