Journal Published Online: 01 October 2006
Volume 3, Issue 9

Basics of Polymeric Scaffolds for Tissue Engineering

CODEN: JAIOAD

Abstract

This review article argues the case that there is a need for careful scaffold science for successful tissue engineering. Polymeric scaffolds should possess certain essential properties. However, these properties are not independent of each other and thus the development of a scaffold requires an optimization process. The article reviews several scaffold fabrication processes to highlight the complexity of the field. Issues related to porosity, permeability, and the need for adequate diffusion characteristics are discussed. Several previous studies on the effects of mixing in bioreactors are reviewed. Lastly, surface modification techniques are presented. In particular, recent work related to glow discharge gas plasma modification of biodegradable polymers is discussed.

Author Information

Agrawal, CM
Biomedical Engineering, College of Engineering, The University of Texas, San Antonio, TX
Carter, J
Biomedical Engineering, College of Engineering, The University of Texas, San Antonio, TX
Ong, JL
Biomedical Engineering, College of Engineering, The University of Texas, San Antonio, TX
Pages: 10
Price: $25.00
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Stock #: JAI100428
ISSN: 1546-962X
DOI: 10.1520/JAI100428