Volume 50, Issue 6 (November 2005)

    Alkaloid Content of the Seeds from Erythroxylum Coca var. Coca

    (Received 9 March 2005; accepted 4 June 2004)

    Published Online: September

    CODEN: JFSOAD

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    Abstract

    Alkaloid extracts from the seeds of Erythroxylum Coca var. Coca grown in the Chapare Valley of Bolivia were subjected to gas and liquid chromatographic-mass spectrometric analyses. Several alkaloids from these seeds were detected and characterized, including methylecgonidine, tropine, 3α-acetoxytropane, ecgonine methyl ester, cuscohygrine, N-norbenzoyltropine, benzoyltropine, hexanoylecgonine methyl ester, cocaine, cis-cinnamoylcocaine, and trans-cinnamoylcocaine. Methylecgonidine was determined to be the primary constituent and not an analytical artifact. Additionally, two significant new uncharacterized alkaloids were established as present. Recent evidence suggests that some cocaine processors are adding this seed extraction material to cocaine extracted from coca leaf and may impact cocaine impurity signature profiles.


    Author Information:

    Casale, JF
    U.S. Department of Justice, Dulles, VA

    Toske, SG
    U.S. Department of Justice, Dulles, VA

    Colley, VL
    U.S. Department of Justice, Dulles, VA


    Stock #: JFS2005121

    ISSN: 0022-1198

    DOI: 10.1520/JFS2005121

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    Author
    Title Alkaloid Content of the Seeds from Erythroxylum Coca var. Coca
    Symposium , 0000-00-00
    Committee E30