Acute Selenium Poisoning: Suicide by Ingestion

    Volume 50, Issue 4 (July 2005)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 25 May 2005

    Page Count: 5


    Hunsaker, DM
    Office of the Chief Medical Examiner, Louisville, Kentucky

    Williams, D
    Emergency Department, Harrison County Hospital, Corydon, Indiana

    Spiller, HA
    Director, Kentucky Regional Poison Control Center Louisville, Kentucky

    (Received 19 June 2004; accepted 5 March 2005)

    Abstract

    Selenium is a ubiquitous element in the environment essential to the human diet and widely utilized in industrial processes. Fatal human selenium intoxication is rare. The authors report a case in which investigators recovered a bottle of gun-bluing agent beside a 24-year-old man. He exhibited signs and symptoms typical of acute selenium intoxication presenting with nausea and vomiting, followed by pulmonary edema and rapid cardiovascular collapse approximately 3 to 4 h after ingestion. Classic electrocardiographic (EKG) changes, which have been reported to occur in acute selenium intoxication, included sinus tachycardia with ST wave alteration. Toxicological results confirmed elevated blood and tissue concentrations. The cause of death was ascribed to acute selenium intoxication, which ensued rapidly after oral consumption. The manner of death was suicide. This case report, which presents an overview of acute and chronic selenium poisoning, underscores the value of thorough toxicologic analyses of tissue and body fluids in humans.


    Paper ID: JFS2004247

    DOI: 10.1520/JFS2004247

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    Author
    Title Acute Selenium Poisoning: Suicide by Ingestion
    Symposium , 0000-00-00
    Committee E30