ISSN: 0022-1198
CODEN: JFSCA
Published Online: 16 February 2004
Page Count: 3

Unusual Association of Three Rare Alleles and a Mismatch in a Case of Paternity Testing
Arseni, A
Istituto di Medicina Legale,

Tagliabracci, A
Istituto di Medicina Legale,

Turchi, C
Istituto di Medicina Legale,

Alessandrini, F
Istituto di Medicina Legale,

Pesaresi, N
Istituto di Medicina Legale,

Onofri, V
Istituto di Medicina Legale,

(Received 10 August 2003; accepted 8 November 2003)

Abstract

This study reports a paternity case analyzed by the AmpℓSTR Identifiler Kit (AB) in which father and daughter shared three rare alleles for D19S433, D18S51 and TH01 microsatellites. The case also showed an apparent exclusion, due to a mutation at the D3S1358 microsatellite. Sequencing analysis was performed to assess the size of the rare alleles and to establish their structure, which revealed some molecular variations in regions flanking the motif repeats.

Keywords:
forensic science, paternity testing, rare alleles, mismatch, STRs, DNA

Paper ID: JFS2003271
DOI: 10.1520/JFS2003271
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