ISSN: 0022-1198
CODEN: JFSCA
Published Online: 19 February 2004
Page Count: 2

Erroneous Gender Identification by the Amelogenin Sex Test
Michael, A
Forensic Biology Laboratory,

Brauner, P
Forensic Biology Laboratory,

(Received 28 June 2003; accepted 30 October 2003)

Abstract

Human gender identification, based on the amelogenin gene, has important applications in forensic casework, prenatal diagnosis, DNA databasing, and blood sample storage. However, we report on the first known case, in the Israeli population, of an amelogenin sex test failure on a phenotypically normal male. He was typed as a female by both the AmpFℓSTR® SGM plus™ and GenePrint™ kits. Subsequent, karyotyping of the soldier's blood sample showed no abnormalities. These results suggest that the determination of sex, based on the amelogenin test, should be interpreted cautiously.

Keywords:
forensic science, amelogenin, SGM plus, GenePrint, FTA, short tandem repeats, polymerase chain reaction

Paper ID: JFS2003223
DOI: 10.1520/JFS2003223
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