ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 March 1998
Page Count: 4

Human Orosomucoid (ORM¹) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains
Reker, G
Institut für Blutgruppenforschung,

Henke, J
Institut für Blutgruppenforschung,

Henke, L
Institut für Blutgruppenforschung,

Dülmer, M
Institut für Blutgruppenforschung,

Nguyen, TT
Institut für Blutgruppenforschung,

(Received 9 June 1997; accepted 10 July 1997)

Abstract

Genetic polymorphism of serum orosomucoid (ORM¹) was investigated in 1072 unrelated German Caucasians using isolectric focusing followed by Western blotting and EIA. The estimated allele frequencies were ORM¹ *F1 = 0,5690, ORM¹ *S = 0,3927, ORM¹ *F2 = 0,0368, ORM¹ *F2S = 0,0009 and ORM¹ *F5 = 0,0005. The method was successfully applied to determine ORM¹ phenotypes in aged blood samples and blood stains. The results indicated that the ORM protein is a informative and remarkably robust blood group system.

Keywords:
forensic science, orosomucoid, ORM1, serum protein, polymorphism, population genetics, bloodstains, aged blood samples

Paper ID: JFS16159J
DOI: 10.1520/JFS16159J
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