Volume 43, Issue 2 (March 1998)

    Human Orosomucoid (ORM1) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains

    (Received 9 June 1997; accepted 10 July 1997)

    Published Online: March

    CODEN: JFSOAD

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    Abstract

    Genetic polymorphism of serum orosomucoid (ORM1) was investigated in 1072 unrelated German Caucasians using isolectric focusing followed by Western blotting and EIA. The estimated allele frequencies were ORM1 *F1 = 0,5690, ORM1 *S = 0,3927, ORM1 *F2 = 0,0368, ORM1 *F2S = 0,0009 and ORM1 *F5 = 0,0005. The method was successfully applied to determine ORM1 phenotypes in aged blood samples and blood stains. The results indicated that the ORM protein is a informative and remarkably robust blood group system.


    Author Information:

    Reker, G
    Institut für Blutgruppenforschung, Köln,

    Henke, J
    Institut für Blutgruppenforschung, Köln,

    Henke, L
    Institut für Blutgruppenforschung, Düsseldorf,

    Dülmer, M
    Institut für Blutgruppenforschung, Köln,

    Nguyen, TT
    Institut für Blutgruppenforschung, Köln,


    Stock #: JFS16159J

    ISSN: 0022-1198

    DOI: 10.1520/JFS16159J

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    Author
    Title Human Orosomucoid (ORM1) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains
    Symposium , 0000-00-00
    Committee E30