Human Orosomucoid (ORM1) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains

    Volume 43, Issue 2 (March 1998)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 March 1998

    Page Count: 4


    Reker, G
    Institut für Blutgruppenforschung, Köln,

    Henke, J
    Institut für Blutgruppenforschung, Köln,

    Henke, L
    Institut für Blutgruppenforschung, Düsseldorf,

    Dülmer, M
    Institut für Blutgruppenforschung, Köln,

    Nguyen, TT
    Institut für Blutgruppenforschung, Köln,

    (Received 9 June 1997; accepted 10 July 1997)

    Abstract

    Genetic polymorphism of serum orosomucoid (ORM1) was investigated in 1072 unrelated German Caucasians using isolectric focusing followed by Western blotting and EIA. The estimated allele frequencies were ORM1 *F1 = 0,5690, ORM1 *S = 0,3927, ORM1 *F2 = 0,0368, ORM1 *F2S = 0,0009 and ORM1 *F5 = 0,0005. The method was successfully applied to determine ORM1 phenotypes in aged blood samples and blood stains. The results indicated that the ORM protein is a informative and remarkably robust blood group system.


    Paper ID: JFS16159J

    DOI: 10.1520/JFS16159J

    ASTM International
    is a member of CrossRef.

    Author
    Title Human Orosomucoid (ORM1) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains
    Symposium , 0000-00-00
    Committee E30