Journal Published Online: 01 March 1998
Volume 43, Issue 2

Human Orosomucoid (ORM ) Subtyping: Further Population Genetic Data and Reports on the Feasibility to Type Aged Blood Samples and Stains

CODEN: JFSCAS

Abstract

Genetic polymorphism of serum orosomucoid (ORM1) was investigated in 1072 unrelated German Caucasians using isolectric focusing followed by Western blotting and EIA. The estimated allele frequencies were ORM1 *F1 = 0,5690, ORM1 *S = 0,3927, ORM1 *F2 = 0,0368, ORM1 *F2S = 0,0009 and ORM1 *F5 = 0,0005. The method was successfully applied to determine ORM1 phenotypes in aged blood samples and blood stains. The results indicated that the ORM protein is a informative and remarkably robust blood group system.

Author Information

Dülmer, M
Institut für Blutgruppenforschung, Köln, Germany
Reker, G
Institut für Blutgruppenforschung, Köln, Germany
Nguyen, TT
Institut für Blutgruppenforschung, Köln, Germany
Henke, L
Institut für Blutgruppenforschung, Düsseldorf, Germany
Henke, J
Institut für Blutgruppenforschung, Köln, Germany
Pages: 4
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Stock #: JFS16159J
ISSN: 0022-1198
DOI: 10.1520/JFS16159J