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    Volume 47, Issue 4 (July 2002)

    Postmortem Concentrations of Citalopram

    (Received 16 February 2002; accepted 8 February 2002)

    Published Online: July

    CODEN: JFSOAD

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    Abstract

    The postmortem concentrations of citalopram in blood, bile, liver, and vitreous humour were investigated in 14 cases using a spe-cially developed high performance liquid chromatography assay. Concentrations from drug and non-drug related deaths were categorized to deter-mine a postmortem therapeutic and toxic range. Therapeutic citalopram concentrations for blood, bile, liver, and vitreous humour ranged to 0.4 mg/L, 2.1 mg/l, 6.6 mg/kg, and 0.2 mg/L, respectively. In one potentially fatal response to citalopram, concentrations were 0.8 mg/L, 6.0 mg/L, 0.3 mg/L for blood, bile and vitreous humour, respectively.


    Author Information:

    McIntyre, IM
    Forensic Toxicologist and Manager of Toxicology, Monash University, Southbank, Victoria

    Lynch, MJ
    Senior Forensic Pathologist, Monash University, Southbank, Victoria

    Anastos, N
    Forensic Toxicologist, Monash University, Southbank, Victoria

    Drummer, OH
    Head of Scientific Services, and Associate Professor of Victorian Institute of Forensic Medicine, Monash University, Southbank, Victoria


    Stock #: JFS15458J

    ISSN: 0022-1198

    DOI: 10.1520/JFS15458J

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    Title Postmortem Concentrations of Citalopram
    Symposium , 0000-00-00
    Committee E30