ISSN: 0022-1198
Page Count: 5

Arab Population Data on the PCR-Based Loci: HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc, and D1S80
Budowle, B
Unit Chief, Forensic Science Research and Training Center, FBI Academy, VA

Hayes, JM
The George Washington University, DC

Freund, M
Head of Forensic Laboratory, Leopold Greenberg Institute of Forensic Medicine,

Abstract

Allele and genotype frequencies for seven polymerase chain reaction (PCR)-based DNA genetic markers were determined in an Arab sample population. The loci analyzed were HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc and D1S80. Results were obtained from the first six loci using the AmpliType HLA-DQα DNA and AmpliType PM PCR Amplification and Typing Kits. The VNTR locus D1S80 PCR product was analyzed by polyacrylamide electrophoresis and silver staining. All loci meet Hardy-Weinberg expectations. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Arab population.

Keywords:
pathology and biology, Arab, population databases, polymerase chain reaction, Hardy-Weinberg, HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc, D1S80

Paper ID: JFS15404J
DOI: 10.1520/JFS15404J
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