Volume 40, Issue 5 (September 1995)

    Gender Identification of Dried Human Bloodstains Using Fluorescence In Situ Hybridization

    (Received 13 October 1994; accepted 1 February 1995)

    CODEN: JFSOAD

      Format Pages Price  
    PDF Version 3 $25   ADD TO CART


    Abstract

    Identification of the gender of an individual(s) from whom a bloodstain is derived represents important evidence in medicolegal cases. The efficacy of fluorescence in situ hybridization (FISH) using chromosome X and Y centromeric probes was tested to determine its ability to identify correctly the gender of extracted dried bloodstains. In this preliminary study, FISH correctly identified the gender of 2-week-old dried bloodstains in prepared mixtures of male-to-female blood as low as 1%. The technique is accurate, rapid, sensitive, easily performed and readily available. This application of FISH as a forensic laboratory technique holds great promise.


    Author Information:

    Geisinger, KR
    Professor and Director of Surgical Pathology and Cytopathology, Bowman Gray School of Medicine of Wake Forest University,

    Pettenati, MJ
    Associate and Assistant Professors, Section on Medical Genetics, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC

    Lantz, PE
    Assistant Professor and Forensic Pathologist, Bowman Gray School of Medicine of Wake Forest University,

    Rao, PN
    Associate and Assistant Professors, Section on Medical Genetics, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC

    Hayworth-Hodge, R
    Molecular Cytogenetic Technologists, Bowman Gray School of Medicine of Wake Forest University,

    Schnell, S
    Molecular Cytogenetic Technologists, Bowman Gray School of Medicine of Wake Forest University,


    Stock #: JFS15403J

    ISSN: 0022-1198

    DOI: 10.1520/JFS15403J

    ASTM International
    is a member of CrossRef.

    Author
    Title Gender Identification of Dried Human Bloodstains Using Fluorescence In Situ Hybridization
    Symposium , 0000-00-00
    Committee E30