The Spectrum of Intramyocardial Small Vessel Disease Associated with Sudden Death

    Volume 47, Issue 2 (March 2002)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 March 2002

    Page Count: 5


    Johnston, B

    Veinot, JP

    Healey, J
    the University of Ottawa Heart Institute, Ottawa, Ontario

    Acharya, V

    (Received 23 July 2001; accepted 18 June 2001)

    Abstract

    Intramyocardial small vessel abnormalities are not commonly recognized. The best known abnormality is fibromuscular dysplasia involving the sinoatrial or atrioventricular nodal arteries. Small vessel disease has been reported as an isolated cardiac anomaly in individuals with sudden death, and may also be associated with other cardiac conditions including hypertrophic cardiomyopathy and mitral valve prolapse. The nature of the association is unknown, and the mechanism causing sudden death is sometimes obscure. We describe pathological changes of the intramyocardial small vessels of three individuals with sudden death. Abnormalities involved small vessels at different levels. In all the cases, the abnormalities were thought to have caused or contributed to the individual's death. The possible mechanisms of this are discussed.


    Paper ID: JFS15263J

    DOI: 10.1520/JFS15263J

    ASTM International
    is a member of CrossRef.

    Author
    Title The Spectrum of Intramyocardial Small Vessel Disease Associated with Sudden Death
    Symposium , 0000-00-00
    Committee E30