Volume 47, Issue 2 (March 2002)

    The Effect of Oleoresin Capsicum “Pepper” Spray Inhalation on Respiratory function

    (Received 23 January 2001; accepted 20 June 2001)

    Published Online: March

    CODEN: JFSOAD

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    Abstract

    We performed a randomized, cross-over controlled trial to assess the effect of Oleoresin capsicum (OC) spray inhalation on respiratory function by itself and combined with restraint. Thirty-five subjects were exposed to OC or placebo spray, followed by 10 min of sitting or prone maximal restraint position (PMRP). Spirometry, oximetry, and end-tidal CO2 levels were collected at baseline and throughout the 10 min. Data were compared between groups (ANOVA) and with predefined normal values. In the sitting position, OC did not result in any significant changes in mean percent predicted forced vital capacity (%predFVC), percent predicted forced expiratory volume in 1 s (%predFEV1), oxygen, or CO2 levels. In PMRP, mean %predFVC and %predFEV1 fell 14.4 and 16.5% for placebo and 16.2 and 19.1% for OC, but were not significantly different by exposure. There was no evidence of hypoxemia or hypercapnia in either groups. OC exposure did not result in abnormal spirometry, hypoxemia, or hypoventilation when compared to placebo in either sitting or PMRP.


    Author Information:

    Vilke, GM
    University of California, San Diego School of Medicine and Medical Center, and the San Diego Regional Public Safety Training Institute, San Diego, CA

    Clausen, J
    University of California, San Diego School of Medicine and Medical Center, and the San Diego Regional Public Safety Training Institute, San Diego, CA

    Schmidt, P
    University of California, San Diego School of Medicine and Medical Center, and the San Diego Regional Public Safety Training Institute, San Diego, CA

    Clark, RF

    Chan, TC
    University of California, San Diego School of Medicine and Medical Center, and the San Diego Regional Public Safety Training Institute, San Diego, CA

    Neuman, T

    Snowden, T
    University of California, San Diego School of Medicine and Medical Center, and the San Diego Regional Public Safety Training Institute, San Diego, CA


    Stock #: JFS15247J

    ISSN: 0022-1198

    DOI: 10.1520/JFS15247J

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    Author
    Title The Effect of Oleoresin Capsicum “Pepper” Spray Inhalation on Respiratory function
    Symposium , 0000-00-00
    Committee E30