ISSN: 0022-1198
CODEN: JFSCA
Page Count: 5

Evaluation of Capillary Electrophoresis Performance Through Resolution Measurements
Buel, E
Laboratory director, forensic chemist III, senior forensic chemist, Vermont Forensic Laboratory, VT

LaFountain, M
Laboratory director, forensic chemist III, senior forensic chemist, Vermont Forensic Laboratory, VT

Schwartz, M
Laboratory director, forensic chemist III, senior forensic chemist, Vermont Forensic Laboratory, VT

Walkinshaw, M
Criminalist II, Tucson Police Dept., AZ

(Received 21 December 1999; accepted 24 May 2000)

Abstract

The application of resolution measurements to an electrophoretic system can give a quantitative analysis of the health of that system. Capillary electrophoresis has become a routine method for the analysis of DNA and resolution measurements can be used to assess the resulting electropherogram. A number of methods are available to evaluate resolution and three methods are detailed in the current work. Parameters such as polymer concentration and column length were also examined in terms of resolution, and changes therein, if these parameters were modified.

Keywords:
forensic science, capillary electrophoresis, DNA, resolution, performance analysis

Paper ID: JFS14968J
DOI: 10.1520/JFS14968J
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