ISSN: 0022-1198
CODEN: JFSCA
Page Count: 10

Population Data on the Thirteen CODIS Core Short Tandem Repeat Loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians
Baumstark, AL
Forensic Science Research and Training Center, FBI Academy, Virginia

Budowle, B
Forensic Science Research and Training Center, FBI Academy, Virginia

Defenbaugh, DA
Forensic Science Research and Training Center, FBI Academy, Virginia

Keys, KM
Forensic Science Research and Training Center, FBI Academy, Virginia

Moretti, TR
Forensic Science Research and Training Center, FBI Academy, Virginia

(Received 21 January 1999; accepted 26 March 1999)

Abstract

Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11, were determined in African American, United States Caucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Based on the exact test, the loci that departed significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p = 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Caucasians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni correction for the number of loci analyzed (i.e., 13 loci per database), these observations are not likely to be significant. There is little evidence for association of alleles between the loci in these databases. The allelic frequency data are similar to other comparable data within the same major population group.

Keywords:
forensic science, Caucasian, African American, Hispanic, Bahamian, Jamaican, Trinidadian, DNA typing, population genetics, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D13S317, D16S539, D18S51D21S11, CODIS core loci

Paper ID: JFS14601J
DOI: 10.1520/JFS14601J
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