Volume 44, Issue 3 (May 1999)

    Japanese Population Study of a Y-Linked Dinucleotide Repeat DNA Polymorphism

    (Received 17 November 1997; accepted 22 September 1998)

    CODEN: JFSOAD

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    Abstract

    A polymorphic CA repeats (YCA II) was previously reported on the human Y chromosome. We have used a simple technique based on polymerase chain reaction amplification followed by native polyacrylamide gel electrophoresis to study the inheritance, the genetic stability, and the allele frequency distribution of this polymorphism in the Japanese. We found seven haplotypes which were tentatively designated as: A[(CA)19/(CA)21], B[(CA)19/(CA)22], C[(CA)19/(CA)23], D[(CA)19/(CA)19], E[(CA)21/(CA)21], F[(CA)22/(CA)22], and G[(CA)23/(CA)23]. The frequencies of these haplotypes were: A, 0.21; B, 0.29; C, 0.37; D, 0.02; E, 0.02; F, 0.07; G, 0.01. There was complete concordance with each father-son pairs. The results indicate the dinucleotide system YCA II is very useful for investigation of forensic samples, especially mixed stains in sexual offence cases.


    Author Information:

    Matsumoto, H
    Nagasaki University School of Medicine, Nagasaki,

    Tsuda, R
    Nagasaki University School of Medicine, Nagasaki,

    Kubo, S
    School of Medicine, The University of Tokusima, Tokusima,

    Tsuruya, S
    Scientific Investigation Laboratory, Nagasaki Pref. Police HQ, Nagasaki,

    Orihara, Y
    Nagasaki University School of Medicine, Nagasaki,


    Stock #: JFS14514J

    ISSN: 0022-1198

    DOI: 10.1520/JFS14514J

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    Author
    Title Japanese Population Study of a Y-Linked Dinucleotide Repeat DNA Polymorphism
    Symposium , 0000-00-00
    Committee E30