ISSN: 0022-1198
CODEN: JFSCA
Page Count: 2

Allele and Genotype Frequencies for the STR Locus D18S51 in a Western German Population
Baasner, A
Institute of Legal Medicine, University of Bonn,

Madea, B
Institute of Legal Medicine, University of Bonn,

(Received 23 March 1998; accepted 13 July 1998)

Abstract

Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. Allele frequencies were determined using PCR for 102 unrelated Germans (Rhine area) for the locus D18S51. Twelve alleles were observed, with frequencies ranging from 0.005 (allele 11) to 0.191 (allele 14). The observed heterozygosity was 0.867, and the power of discrimination was 0.968. There was no deviation from expectations under Hardy-Weinberg assumptions (P = 0.451).

Keywords:
forensic science, DNA typing, short tandem repeat, D18S51, allele frequencies, Hardy-Weinberg equilibrium, population genetics, Germany

Paper ID: JFS14485J
DOI: 10.1520/JFS14485J
ASTM International is a member of CrossRef.