ISSN: 0022-1198
CODEN: JFSCA
Page Count: 4

Use of Combined Frequencies for RFLP and PCR Based Loci in Determining Match Probability
Giles, BA
Forensic science supervisor, laboratory manager, and forensic scientist, Pennsylvania State Police Greensburg Regional Laboratory, PA

Budowle, B
Unit chief, Forensic Science Research and Training Center, FBI Academy, VA

Basten, CJ
Department of Statistics, North Carolina State University, NC

Tomsey, CS
DNA Laboratory manager, Pennsylvania State Police Bureau of Forensics and Criminal Identification, Forensics Division, PA

Ermlick, S
Forensic science supervisor, laboratory manager, and forensic scientist, Pennsylvania State Police Greensburg Regional Laboratory, PA

Gotwald, S
Forensic science supervisor, laboratory manager, and forensic scientist, Pennsylvania State Police Greensburg Regional Laboratory, PA

(Received 3 February 1998; accepted 29 June 1998)

Abstract

Statistical analysis was performed on a subset of the Pennsylvania State Police Caucasian, African American and Hispanic database for the purpose of determining Hardy-Weinberg equilibrium and associations across the RFLP loci D1S7, D2S44, D4S139, D5S110, D10S28 and D17S79 and the PCR-based loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc. Overall, the statistical results are consistent with a population in equilibrium both within and between loci. The assumption for independence is valid.

Keywords:
forensic science, DNA typing, restriction fragment length polymorphism, D1S7, D2S44, D4S139, D5S110, D10S28, D17S79, HLA-DQA1, LDLR, GYPA, Gc, D7S8, HBGG, population genetics, Hardy-Weinberg equilibrium, polymerase chain reaction, linkage equilibrium, independence

Paper ID: JFS14469J
DOI: 10.1520/JFS14469J
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