Volume 43, Issue 4 (July 1998)

    Italian Population Data on the Polymarker System and on the Five Short Tandem Repeat Loci CSF1PO, TPOX, TH01, F13B, and vWA

    (Received 14 May 1997; accepted 5 November 1997)

    CODEN: JFSOAD

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    Abstract

    A population study on five short tandem repeat (STR) loci and five sequence specific polymorphism loci was performed on unrelated Italian Caucasians. Separation and detection of the amplified STR fragments were carried out by high resolution vertical denaturing polyacrylamide gel electrophoresis (PAGE) and silver staining, respectively. The sequence specific loci were analyzed using the AmpliType PM Typing Kit (Perkin Elmer, Foster City, CA). All loci, except Gc (p = 0.031), meet Hardy-Wienberg expectations. In addition, there is no evidence for association of alleles between pairs of loci. The combined power of discrimination for the five STR loci is 0.9999862 and for the PM loci is 0.99503. The results suggest that these loci may be useful for human identification cases in Italy.


    Author Information:

    Virgili, A
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Budowle, B
    Program manager for DNA Research, Forensic Science Research and Training Center, FBI Academy, Quantico, VA

    Vecchio, C
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Zanon, C
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Lago, G
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Albonici, L
    Professor of pathology and researcher, University of Rome, Tor Vergata,

    Garofano, L
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Pizzamiglio, M
    Servizio Carabinieri Investigazioni Scientifiche, Parma,

    Manzari, V
    Professor of pathology and researcher, University of Rome, Tor Vergata,


    Stock #: JFS14315J

    ISSN: 0022-1198

    DOI: 10.1520/JFS14315J

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    Author
    Title Italian Population Data on the Polymarker System and on the Five Short Tandem Repeat Loci CSF1PO, TPOX, TH01, F13B, and vWA
    Symposium , 0000-00-00
    Committee E30