ISSN: 0022-1198
CODEN: JFSCA
Page Count: 5

Distribution of HLA-DQα and Polymarker (LDLR, GC, GYPA, HBGG, and D7S8) Alleles in Arab and Pakistani Populations Living in Abu Dhabi, United Arab Emirates
Budowle, B
Forensic Science Research and Training Center, FBI Academy, VA

Novick, GE
Indianapolis-Marion County Forensic Services Agency, IN

Caruso, J
Indianapolis-Marion County Forensic Services Agency, IN

Tahir, MA
Indianapolis-Marion County Forensic Services Agency, IN

Aziz, N
King Edward Medical College, Pakistan

(Received 1 July 1996; accepted 3 December 1996)

Abstract

Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.

Keywords:
forensic science, DNA typing, polymerase chain reaction, HLA-DQA1, LDLR, GC, GYPA, HBGG, D7S8, polymarker, population genetics, allele frequencies, Arab, Pakistani

Paper ID: JFS14230J
DOI: 10.1520/JFS14230J
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