Journal Published Online: 01 July 1997
Volume 42, Issue 4

Rapid Screening of Multiple Forensic Stains by SSCP Analysis of HLA-DQα Amplification Products

CODEN: JFSCAS

Abstract

Single strand conformation polymorphism (SSCP) analysis was performed with HLA-DQα amplification products. The various HLA-DQα genotypes reveal different SSCP patterns. These are reproducible in DNA preparations from unrelated persons with identical HLA-DQα genotype. However, in one of the more frequent HLA-DQα genotypes (1.1/4) two variant SSCP patterns were observed. SSCP analysis allows rapid low-cost screening of many specimens and is an alternative discrimination test of stains beside reverse dot blot hybridization.

Author Information

Kreike, J
Institut für Gerichtliche Medizin, Universität Wien, Wien, Austria
Lehner, A
Institut für Gerichtliche Medizin, Universität Wien, Wien, Austria
Pages: 3
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Stock #: JFS14189J
ISSN: 0022-1198
DOI: 10.1520/JFS14189J