Volume 42, Issue 4 (July 1997)

    Rapid Screening of Multiple Forensic Stains by SSCP Analysis of HLA-DQα Amplification Products

    (Received 9 April 1996; accepted 18 November 1996)

    CODEN: JFSOAD

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    Abstract

    Single strand conformation polymorphism (SSCP) analysis was performed with HLA-DQα amplification products. The various HLA-DQα genotypes reveal different SSCP patterns. These are reproducible in DNA preparations from unrelated persons with identical HLA-DQα genotype. However, in one of the more frequent HLA-DQα genotypes (1.1/4) two variant SSCP patterns were observed. SSCP analysis allows rapid low-cost screening of many specimens and is an alternative discrimination test of stains beside reverse dot blot hybridization.


    Author Information:

    Lehner, A
    Institut für Gerichtliche Medizin, Universität Wien, Wien,

    Kreike, J
    Institut für Gerichtliche Medizin, Universität Wien, Wien,


    Stock #: JFS14189J

    ISSN: 0022-1198

    DOI: 10.1520/JFS14189J

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    Title Rapid Screening of Multiple Forensic Stains by SSCP Analysis of HLA-DQα Amplification Products
    Symposium , 0000-00-00
    Committee E30