ISSN: 0022-1198
CODEN: JFSCA
Page Count: 4

Distribution of Types for Six PCR-Based Loci; LDLR, GYPA, HBGG, D7S8, GC and HLA-DQA1 in Central Pyrenees and Teruel (Spain)
Bell, B
Research scientists and professor of the Department of Legal Medicine, Facultad de Medicina, University of Zaragoza,

Budowle, B
Unit chief, Forensic Science Research and Training Center, FBI Academy, VA

Martinez-Jarreta, B
Research scientists and professor of the Department of Legal Medicine, Facultad de Medicina, University of Zaragoza,

Abecia, E
Research scientists and professor of the Department of Legal Medicine, Facultad de Medicina, University of Zaragoza,

Castellano, M
Research scientists and professor of the Department of Legal Medicine, Facultad de Medicina, University of Zaragoza,

Casalod, Y
Research scientists and professor of the Department of Legal Medicine, Facultad de Medicina, University of Zaragoza,

(Received 2 July 1996; accepted 30 September 1996)

Abstract

The PCR-based DNA loci LDLR, GYPA, HBGG, D7S8, GC and HLA DQA1 are widely used in forensic casework analyses. Population data on the distribution of allele frequencies are desired to estimate the rarity of a DNA profile. We studied the allele distributions at these forensically important DNA markers in two Spanish populations (Central Pyrenees and Teruel). Results were in agreement with Hardy-Weinberg expectations. Furthermore, there was little evidence for departures from expectation of independence between loci within the two sample populations. Tests for homogeneity were carried out between the two Spanish populations and a U.S. Caucasian population.

Keywords:
forensic science, DNA typing, population genetics, LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, Central Pyrenees, Teruel, Spain

Paper ID: JFS14158J
DOI: 10.1520/JFS14158J
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