ISSN: 0022-1198
CODEN: JFSCA
Page Count: 5

Genetic Variations at Four Tetrameric Tandem Repeat Loci in Korean Population
Koo, BS
Laboratory of DNA analysis and Criminalistics Instruction Division, the Supreme Public Prosecutor's Office,

Budowle, B
Forensic Science Research and Training Center, FBI Academy, VA

Rho, HM
Seoul National University,

Kim, SH
Inje University,

Park, SJ
Inje University,

Lee, SW
Laboratory of DNA analysis and Criminalistics Instruction Division, the Supreme Public Prosecutor's Office,

Lee, WG
Seoul National University,

(Received 14 March 1996; accepted 1 May 1996)

Abstract

Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.

Keywords:
forensic science, DNA typing, FES/FPS, FOLP23, GABRB15, CYAR04, short tandem repeat, Hardy-Weinberg equilibrium, population genetics, Korea

Paper ID: JFS14081J
DOI: 10.1520/JFS14081J
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