Volume 41, Issue 1 (January 1996)

    HUMTH01 Validation Studies: Effect of Substrate, Environment, and Mixtures

    (Received 17 February 1995; accepted 23 June 1995)

    CODEN: JFSOAD

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    Abstract

    New DNA typing methods need to be thoroughly validated prior to use in forensic investigations. This includes determining the effects different sample conditions have on the typeability of those samples. Biological samples routinely encountered in forensic case work were exposed to a series of different substrates, environmental conditions, and mixtures and typed for the STR HUMTH01 using PCR. None of the conditions resulted in a false typing or preferential allele amplification. It is demonstrated that the application of HUMTH01 typing methods in forensic case work can be reliable, robust, and efficient.


    Author Information:

    Andrew, IR
    Forensic Officer, Premier Caseworker, and Forensic Officers, Victoria Forensic Science Centre (VFSC) Forensic Drive, Macleod, Victoria

    Hedley, JA
    Forensic Officer, Premier Caseworker, and Forensic Officers, Victoria Forensic Science Centre (VFSC) Forensic Drive, Macleod, Victoria

    van Oorschot, RAH
    Forensic Officer, Premier Caseworker, and Forensic Officers, Victoria Forensic Science Centre (VFSC) Forensic Drive, Macleod, Victoria

    Gutowski, SJ
    Forensic Officer, Premier Caseworker, and Forensic Officers, Victoria Forensic Science Centre (VFSC) Forensic Drive, Macleod, Victoria

    Robinson, SL
    Forensic Officer, Premier Caseworker, and Forensic Officers, Victoria Forensic Science Centre (VFSC) Forensic Drive, Macleod, Victoria


    Stock #: JFS13912J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13912J

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    Author
    Title HUMTH01 Validation Studies: Effect of Substrate, Environment, and Mixtures
    Symposium , 0000-00-00
    Committee E30