Volume 40, Issue 1 (January 1995)

    Evaluation of the Abuscreen Online Assay for Amphetamines on the Hitachi 737: Comparison with EMIT and GC/MS Methods

    (Received 24 February 1994; accepted 25 May 1994)

    CODEN: JFSOAD

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    Abstract

    The performance of the ONLINE Assay for Amphetamines on the Hitachi 737 was compared to the Syva Emit d.a.u. Assay and GC/MS. Randomly screened (n = 2964) patient urine samples were assayed using ONLINE and Emit d.a.u. assays concurrently, using d-amphetamine, 1000 ng/mL and d-methamphetamine, 1000 ng/mL as the screening cutoff for ONLINE and Emit d.a.u. assays, respectively. All presumptive positives were confirmed by GC/MS. The specificity was 99% (2937/2964) for ONLINE and 97% (2873/2964) for Emit. Agreement with GC/MS was 80% (110/137) for ONLINE and 55% (110/201) for Emit.


    Author Information:

    Escoto, B
    Group Leader, Toxicology Section, Damon Reference Laboratories, Newbury Park, CA

    Baker, DP
    Technical Director, Utak Laboratories, Inc., Valencia, CA

    Caldarone, ME
    Group Leader, Toxicology Section, Damon Reference Laboratories, Newbury Park, CA

    Murphy, MS
    Senior Laboratory Assistants, Toxicology Section, Damon Reference Laboratories, Newbury Park, CA

    Shepp, PF
    Senior Laboratory Assistants, Toxicology Section, Damon Reference Laboratories, Newbury Park, CA

    Salamone, SJ
    Director of Research and Product Development, International Drug Monitoring Business Unit, Roche Diagnostic Systems, Somerville, NJ

    Royo, VR
    Senior Laboratory Assistants, Toxicology Section, Damon Reference Laboratories, Newbury Park, CA


    Stock #: JFS13771J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13771J

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    Title Evaluation of the Abuscreen Online Assay for Amphetamines on the Hitachi 737: Comparison with EMIT and GC/MS Methods
    Symposium , 0000-00-00
    Committee E30