Analysis of HLA DQα Allele and Genotype Frequencies in Populations from Florida

    Volume 39, Issue 3 (May 1994)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 12


    Crouse, CA
    Forensic Scientists, Palm Beach County Sheriff's Crime Laboratory, West Palm Beach, FL

    Nippes, DC
    Laboratory Director, Regional Crime Laboratory at Indian River Community College, Fort Pierce, FL

    Glidewell, DE
    Forensic Scientists, Palm Beach County Sheriff's Crime Laboratory, West Palm Beach, FL

    Coffman, D
    Senior Crime Laboratory Analysts, Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL

    Barnes, KS
    Senior Crime Laboratory Analysts, Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL

    Ginsberg, L
    Senior Crime Laboratory Analyst, Florida Department of Law Enforcement Crime Laboratory, Pensacola, FL

    Livingston, SH
    Senior Crime Laboratory Analysts, Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL

    Celia Hutto, S
    Associate Professor, Univ. of Miami School of Medicine, Miami

    Feuer, WJ
    Research Associate, Univ. of Miami School of Medicine, Miami, FL

    (Received 7 June 1993; accepted 15 November 1993)

    Abstract

    HLA DQα allele and genotype frequencies for Caucasian, African American, Haitian, and Hispanic populations in Florida have been estimated. The Florida laboratories involved in these studies collected donor samples from a variety of sites including clinical laboratories, victim and suspect standards, blood banks, county jail detainees, and laboratory personnel. We have determined that the Caucasian and African American DQα genotype frequencies do not deviate significantly from Hardy-Weinberg expectations and as a result of this heterogeneity analyses, data from the four Florida Caucasian populations may be combined and data from the four Florida African American populations may be combined to form two large HLA DQα genotype frequency databanks. Further, data from the Florida Haitian population may be combined with the Florida African American population. Comparison of the combined Florida Caucasian populations, combined Florida African American populations, the Palm Beach Sheriff's Office (PBSO) Hispanic, and PBSO Haitian population with other databases does not support combination because allele frequency distributions are heterogenous.


    Paper ID: JFS13650J

    DOI: 10.1520/JFS13650J

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    Author
    Title Analysis of HLA DQα Allele and Genotype Frequencies in Populations from Florida
    Symposium , 0000-00-00
    Committee E30