Journal Published Online: 01 May 1994
Volume 39, Issue 3

Analysis of HLA DQα Allele and Genotype Frequencies in Populations from Florida

CODEN: JFSCAS

Abstract

HLA DQα allele and genotype frequencies for Caucasian, African American, Haitian, and Hispanic populations in Florida have been estimated. The Florida laboratories involved in these studies collected donor samples from a variety of sites including clinical laboratories, victim and suspect standards, blood banks, county jail detainees, and laboratory personnel. We have determined that the Caucasian and African American DQα genotype frequencies do not deviate significantly from Hardy-Weinberg expectations and as a result of this heterogeneity analyses, data from the four Florida Caucasian populations may be combined and data from the four Florida African American populations may be combined to form two large HLA DQα genotype frequency databanks. Further, data from the Florida Haitian population may be combined with the Florida African American population. Comparison of the combined Florida Caucasian populations, combined Florida African American populations, the Palm Beach Sheriff's Office (PBSO) Hispanic, and PBSO Haitian population with other databases does not support combination because allele frequency distributions are heterogenous.

Author Information

Crouse, CA
Palm Beach County Sheriff's Crime Laboratory, West Palm Beach, FL
Feuer, WJ
Univ. of Miami School of Medicine, Miami, FL
Nippes, DC
Regional Crime Laboratory at Indian River Community College, Fort Pierce, FL
Celia Hutto, S
Univ. of Miami School of Medicine, FL
Barnes, KS
Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL
Coffman, D
Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL
Livingston, SH
Florida Department of Law Enforcement Crime Laboratory, Tallahassee, FL
Ginsberg, L
Florida Department of Law Enforcement Crime Laboratory, Pensacola, FL
Glidewell, DE
Palm Beach County Sheriff's Crime Laboratory, West Palm Beach, FL
Pages: 12
Price: $25.00
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Stock #: JFS13650J
ISSN: 0022-1198
DOI: 10.1520/JFS13650J