Journal Published Online: 01 January 1994
Volume 39, Issue 1

The Determination of Anabolic Steroids by MECC, Gradient HPLC, and Capillary GC

CODEN: JFSCAS

Abstract

Methodologies are presented for the qualitative and quantitative determinations of anabolic steroids in forensic exhibits using micellar electrokinetic capillary chromatography (MECC), high performance liquid chromatography (HPLC) and capillary gas chromatography (GC). Analyses of representative pharmaceutical dosage forms (including a commercial aqueous suspension, a commercial tablet, several commercial oil samples and various simulated dosage units) were performed using a simple, one step quantitative extraction procedure with methanol. Good agreement was obtained between all three techniques. Retention, migration and linearity data are presented and compared for over twenty anabolic steroids commonly encountered in forensic exhibits. A principal component analysis study confirmed the orthogonality of the three techniques.

Author Information

Lurie, IS
Special Testing and Research Laboratory, Drug Enforcement Administration, McLean, VA
Sperling, AR
Special Testing and Research Laboratory, Drug Enforcement Administration, McLean, VA
Meyers, RP
Special Testing and Research Laboratory, Drug Enforcement Administration, McLean, VA
Pages: 12
Price: $25.00
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Stock #: JFS13572J
ISSN: 0022-1198
DOI: 10.1520/JFS13572J