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    Volume 38, Issue 6 (November 1993)

    Evaluation of HLA in Detection of Non-Parentage Among Known False Trios

    (Received 22 April 1992; accepted 17 May 1993)

    CODEN: JFSOAD

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    Abstract

    This paternity study was performed with trios in which the putative father was not the biological father (NBF), in order to evaluate the effectiveness of HLA-A and -B phenotyping for routine testing.

    All 372 generated trios had ABO, Rh, MNS, Kell, Duffy, Kidd and HLA (A and B) systems tested.

    HLA-A and -B phenotyping directly excluded 81.73% of NBF. Red blood cell markers excluded 8.82% of NBF missed by HLA; only 0.81% of NBF were not identified by the markers used.

    Each laboratory engaged in disputed paternity testing should evaluate its actual performance in detecting non-biological fathers and its exclusion rates in real trios. These data together can be used as a guide of mother's reliability.


    Author Information:

    Salaru, NNR
    University of São Paulo, São Paulo,


    Stock #: JFS13554J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13554J

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    Author
    Title Evaluation of HLA in Detection of Non-Parentage Among Known False Trios
    Symposium , 0000-00-00
    Committee E30